Research ActivitiesRESEARCH ACTIVITIES

Cutting-edge cardiovascular surgery research that
contributes to medical advancement and provides better treatment for patients

Graduate Student Recruitment

The Department of Cardiovascular Surgery at Okayama University Graduate School
is recruiting graduate students.

Research Projects

Cutting-edge cardiovascular surgery research projects

Portable Ex-Situ Perfusion Machine with Functional Evaluation System for Donor Hearts after Circulatory Death

OResearch Objective

To develop a system that can mount DCD hearts to existing ECMO for perfusion, cardiac function evaluation, and transport

AActivities

Animal experiments

SSocial Impact

Aiming to increase the number of heart transplants using DCD hearts

Investigation of Changes in Gut Microbiota Composition in Cyanotic Congenital Heart Disease and Its Impact on Cardiovascular Events

OResearch Objective

To clarify changes in perioperative gut microbiota composition and verify their impact on cardiovascular events

AActivities

Specimen analysis

SSocial Impact

To verify the possibility that gut microbiota affects perioperative course

Elucidation of Pathogenesis of Right Ventricular Outflow Tract Stenosis in Tetralogy of Fallot and Development of Prognostic Markers

OResearch Objective

Little is known about why and how congenital heart disease occurs. Through genetic analysis of heart tissue, focusing on Tetralogy of Fallot, we aim to elucidate the mechanisms of disease development. This could lead to the development of new treatments for congenital heart disease in the future.

AActivities

Cardiac cell culture, genetic analysis of myocardial specimens, and identification of disease-causing genes

SSocial Impact

We will advance research to help patients with congenital heart disease, including those with Tetralogy of Fallot, live longer and healthier lives.

Investigation of Optimal Left Ventricular Assist Device for Fontan Circulation Failure

OResearch Objective

To clarify under what conditions left ventricular assist devices show hemodynamic improvement effects as treatment for acute exacerbation of Fontan failure

AActivities

Using a pig Fontan circulation model to verify conditions under which circulatory failure can be improved by left ventricular assist

SSocial Impact

Expected to clarify conditions under which left ventricular assist is effective and improve treatment strategies

Study of Serotonin Dynamics During Ischemia-Reperfusion Using Cardiac Microdialysis

OResearch Objective

To contribute to the development of treatments that reduce infarct size in ischemic heart disease by studying serotonin dynamics during ischemia-reperfusion. Using cardiac microdialysis to analyze biochemical changes during ischemia in detail.

AActivities

In experimental models using 12-week rats, placing probes in the heart to confirm and evaluate drug effects and degree of myocardial damage

SSocial Impact

Expected to improve prognosis of heart disease patients through establishment of new treatment strategies for infarct size reduction in ischemic heart disease

Development of Protein Adsorption Control Technology Using Multimodal Diamond-like Carbon (DLC) Coating and Medical Applications

OResearch Objective & Background

When foreign objects are implanted in the body, protein adsorption occurs first, which determines subsequent cellular responses and immune reactions. Therefore, technology to freely control protein adsorption is useful for developing new medical devices. Diamond-like Carbon (DLC) is a carbon material that can impart various functions and has excellent biocompatibility. This research aims to establish protein adsorption control methods using DLC and apply them to medical devices.

AActivities

Elucidate the regularity of protein adsorption on DLC surfaces and consider practical applications to medical devices and research devices based on the obtained findings.

SSocial Impact & Future Expectations

DLC-based protein adsorption control technology will enable the design and development of biointerfaces as needed. The findings from this research are expected to have a significant impact on both medicine and research.

Research Participants Wanted

We are looking for people interested in cutting-edge cardiovascular surgery research.
Would you like to contribute to medical advancement together?

Please feel free to contact us for details

Graduate Student Introduction

Introduction of graduate students involved in research

I

Dr. Inoue

Enjoys CABG and large to small vessel anastomosis.

Serves as Chugoku-Shikoku representative in young physician-led organizations at conferences.

S

Dr. Suzuki

Aspiring pediatric cardiac surgeon, moved from Hokkaido to Okayama.

Currently exploring study abroad opportunities.

K

Dr. Kishi

Quiet city boy.

Father of two children, currently conducting research.

K

Dr. Kurata

From Iwakuni, famous for Kintaikyo Bridge.

Was in the baseball club during university and threw breaking balls.

T

Dr. Tokuda

Badminton champion at Western Medical University.

Kyushu gentleman who is kind to everyone.

Y

Dr. Yoshida

Entered graduate school this year.

Sets hair every day. 5th dan in kendo.

Would you like to participate in research?

Please feel free to contact us

Contact by Phone

Okayama University Cardiovascular Surgery

086-235-7359

About Research Participation

We also accept consultations about
research participation and visits at any time

🔬 Let's open the future of medicine with cutting-edge research.
We look forward to your participation.